Hello,
I'm unable to upgrade the Giorgio Research Institute into the Center for Artificial Intelligence as well as a few other buildings.
I've got all the resources, techs and bots to do so yet I'm somehow unable to upgrade them without deleting the building and then building the upgraded version.
I've also noticed a bug when upgrading the cloning facility into the advanced cloning facility. This bug occurs when the building has been orientated from the original orientation and then once you start the upgrade it flips back to the original orientation. Then after it's finished building it then changes orientation once again.