I am experiencing a bug where, whenever a new building is placed, colonists would begin to lose their jobs. Whenever I click on a building, the number of workers appears as normal, but if I view the worker list, there are way fewer workers than should be. The platform I'm using is Windows 10, and the game is running on version 0.45.0.
https://www.my-colony.com/colonies/JZDNwRWX/
Yes its a known bug. Just leave the game for a while let the engine do its work. If you have enough workers, high health score, high happiness, high approval rating all is safe then. If the problem persists, you could always do hard reload.. works everytime for me.